JMJD4

Across TCGA patient cohorts, JMJD4 RNA expression is significantly associated with the protein abundance of many other proteins, with 12,253 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible JMJD4-associated proteins across cancer lineages are PARP1, GATAD2B, and RPRD2. Each is linked with JMJD4 in more than 7 cancer types. Because this analysis shows association rather than direction, both JMJD4-to-partner and partner-to-JMJD4 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, JMJD4 versus PARP1 in LSCC, with a Pearson correlation of 0.57.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (JMJD4→partner) and Y-score (partner→JMJD4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	PARP1 →	+0.422	+0.396	<.001	<.001	3	8
BRCA	GATAD2B →	+0.366	+0.706	<.001	<.001	3	8
LSCC	RPRD2 →	+0.338	+0.430	<.001	<.001	3	7
BRCA	C1orf35 →	+0.513	+0.624	<.001	<.001	3	7
HNSC	HNRNPU →	+0.283	+0.816	<.001	<.001	3	6
HNSC	ARID4B →	+0.314	+0.926	<.001	<.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 12,253 associations by consensus.

JMJD4 vs PARP1 — LSCC

Explore this scatter interactively →