JMJD4

Across TCGA patient cohorts, JMJD4 protein abundance is significantly associated with the RNA expression of many other genes, with 12,304 significant associations in total. GBM shows the largest number of these associations.

The most reproducible JMJD4-associated genes across cancer lineages are KIAA0586, RNF157, and METTL3. Each is linked with JMJD4 in more than 2 cancer types. Because this analysis shows association rather than direction, both JMJD4-to-partner and partner-to-JMJD4 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, JMJD4 versus KIAA0586 in OV, with a Pearson correlation of 0.55.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (JMJD4→partner) and Y-score (partner→JMJD4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	KIAA0586 →	+0.978	+0.269	<.001	.004	3	2
GBM	RNF157 →	-0.806	-0.258	<.001	<.001	3	2
GBM	METTL3 →	-0.365	-0.224	<.001	.003	3	2
BRCA	LMAN2 →	-0.428	-0.281	.002	<.001	3	2
LSCC	HARS1 →	-0.265	-0.249	.005	.003	3	2
BRCA	PRR15 →	-1.533	-0.412	.002	<.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 12,304 associations by consensus.

JMJD4 vs KIAA0586 — OV

Explore this scatter interactively →