JMJD1C

RNA expression — cross-omics
Cross-omicsRNA → FUNCTION-RNACell-linePairwise association · TCGA cohorts

Across TCGA cell cohorts, JMJD1C RNA expression is significantly associated with the go_rna of many other GO terms, with 3,739 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible JMJD1C-associated GO terms across cancer lineages are Establishment of mitotic sister chromatid cohesion, Regulation of maintenance of sister chromatid cohesion, and Regulation of maintenance of mitotic sister chromatid cohesion. Each is linked with JMJD1C in more than 11 cancer types. Because this analysis shows association rather than direction, both JMJD1C-to-partner and partner-to-JMJD1C results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Establishment of mitotic sister chromatid cohesion grouped by JMJD1C-low versus JMJD1C-high in SKIN.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (JMJD1C→partner) and Y-score (partner→JMJD1C) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner GO termX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
SKINEstablishment of mitotic sister chromatid cohesion →+0.102+0.757<.001.001312
BLOOD_MyelomaRegulation of maintenance of sister chromatid cohesion →+0.098+1.086<.001<.001312
BLOOD_MyelomaRegulation of maintenance of mitotic sister chromatid cohesion →+0.098+1.086<.001<.001312
URINARY_TRACTProtein localization to chromosome, telomeric region →+0.101+0.711.003.002312
BLOOD_MyelomaPositive regulation of mitochondrial ATP synthesis coupled electron transport →+0.113+0.838.006.001311
LARGE_INTESTINERegulation of centrosome cycle →+0.089+0.738<.001<.001311
Each partner links to its Q-omics profile. Showing the 6 strongest of 3,739 associations by consensus.

Establishment of mitotic sister chromatid cohesion by JMJD1C expression — SKIN

Box plot of Establishment of mitotic sister chromatid cohesion in JMJD1C-low vs JMJD1C-high samples in SKIN.

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Exploration