JMJD1C

Across TCGA cell cohorts, JMJD1C mutation is significantly associated with the RNA expression of many other genes, with 1,264 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible JMJD1C-associated genes across cancer lineages are TRMU, ADNP2, and B3GNT4. Each is linked with JMJD1C in more than 3 cancer types. Because this analysis shows association rather than direction, both JMJD1C-to-partner and partner-to-JMJD1C results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, TRMU grouped by JMJD1C-low versus JMJD1C-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (JMJD1C→partner) and Y-score (partner→JMJD1C) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	TRMU →	+0.534	+1.628	<.001	.007	3	3
LARGE_INTESTINE	ADNP2 →	+0.634	+2.043	.001	.001	3	3
LARGE_INTESTINE	B3GNT4 →	+0.651	+3.584	<.001	<.001	2	4
LARGE_INTESTINE	KLHL11 →	+0.747	+3.584	<.001	<.001	3	3
URINARY_TRACT	ZSCAN10 →	+0.077	+3.399	.003	.006	3	2
URINARY_TRACT	SAXO1 →	+0.052	+2.584	.003	.009	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,264 associations by consensus.

TRMU by JMJD1C expression — LARGE_INTESTINE

Explore this box plot interactively →