JMJD1C-AS1

Across TCGA pan-cancer cohorts, JMJD1C-AS1 RNA is linked to patient survival in 21 of 34 cancer types, making it the most broadly survival-associated JMJD1C-AS1 data layer.

The strongest signal is observed in adrenocortical carcinoma (ACC), where higher JMJD1C-AS1 RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated JMJD1C-AS1 expression acts as an unfavorable survival marker, although some lineages such as LGG and LUAD show a favorable association.

ACC, KIRP, and UVM are the cancer types where JMJD1C-AS1 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
ACC	DFS	Median	All	0.227	0.663	<.001	107	view →
KIRP	OS	Median	All	0.577	0.769	<.001	74	view →
UVM	DFS	Median	All	0.329	0.766	<.001	52	view →
LGG	OS	Median	All	0.874	0.742	<.001	41	view →
LUSC	DFS	Median	All	0.697	0.794	.002	40	view →
LUAD	DFS	Median	IV	0.864	0.486	.005	24	view →
KICH	DFS	Median	III,IV	0.374	0.901	.009	20	view →
UCS	OS	Median	All	0.494	0.172	.002	16	view →
GBM	DFS	Tertile	All	0.324	0.193	.014	12	view →
THCA	OS	Tertile	All	0.821	1.000	.016	12	view →
BLCA	DFS	Median	All	0.689	0.550	.007	11	view →
HNSC	DFS	Median	All	0.628	0.468	.017	7	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 21 lineages.

JMJD1C-AS1–ACC (DFS)

Open the ACC breakdown →