JKAMP

Across TCGA patient cohorts, JKAMP protein abundance is significantly associated with the RNA expression of many other genes, with 865 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible JKAMP-associated genes across cancer lineages are GRK3, ATG4A, and SLC25A14. Each is linked with JKAMP in more than 1 cancer types. Because this analysis shows association rather than direction, both JKAMP-to-partner and partner-to-JKAMP results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, JKAMP versus GRK3 in BRCA, with a Pearson correlation of 0.55.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (JKAMP→partner) and Y-score (partner→JKAMP) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	GRK3 →	+1.018	+0.732	.001	.002	3	1
BRCA	ATG4A →	+0.414	+0.457	.003	.009	3	1
BRCA	SLC25A14 →	+0.413	+0.493	.009	.004	3	1
BRCA	SYTL4 →	+1.776	+0.742	<.001	.003	3	1
BRCA	FOXF1 →	+0.288	+0.478	.004	.004	3	1
BRCA	METRN →	+2.350	+0.556	.005	<.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 865 associations by consensus.

JKAMP vs GRK3 — BRCA

Explore this scatter interactively →