JCHAIN

Across TCGA patient cohorts, JCHAIN RNA expression is significantly associated with the RNA expression of many other genes, with 11,448 significant associations in total. ESCA shows the largest number of these associations.

The most reproducible JCHAIN-associated genes across cancer lineages are MZB1, SIT1, and CD27. Each is linked with JCHAIN in more than 33 cancer types. Because this analysis shows association rather than direction, both JCHAIN-to-partner and partner-to-JCHAIN results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, JCHAIN versus MZB1 in SKCM, with a Pearson correlation of 0.92.

RNA expression associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (JCHAIN→partner) and Y-score (partner→JCHAIN) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKCM	MZB1 →	+3.855	+4.849	<.001	<.001	3	34
SKCM	SIT1 →	+2.245	+4.123	<.001	<.001	3	33
SKCM	CD27 →	+2.631	+4.209	<.001	<.001	3	33
SCLC	JAML →	+1.803	+3.022	<.001	<.001	3	33
SKCM	LCK →	+2.374	+4.235	<.001	<.001	3	33
SKCM	CD247 →	+1.911	+4.022	<.001	<.001	3	33

Each partner links to its Q-omics profile. Showing the 6 strongest of 11,448 associations by consensus.

JCHAIN vs MZB1 — SKCM

Explore this scatter interactively →