JCHAIN

RNA expression — cross-omics
Cross-omicsRNA → PROTEIN-MSPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, JCHAIN RNA expression is significantly associated with the protein abundance of many other proteins, with 17,596 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible JCHAIN-associated proteins across cancer lineages are MZB1, SEPTIN1, and CASP1. Each is linked with JCHAIN in more than 9 cancer types. Because this analysis shows association rather than direction, both JCHAIN-to-partner and partner-to-JCHAIN results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, JCHAIN versus MZB1 in OV, with a Pearson correlation of 0.75.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (JCHAIN→partner) and Y-score (partner→JCHAIN) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner proteinX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
OVMZB1 →+1.515+3.540<.001<.001310
LSCCSEPTIN1 →+0.795+1.637<.001<.001310
OVCASP1 →+0.902+3.734<.001<.00139
GBMCD2 →+0.908+2.175.005<.00139
OVCD38 →+0.936+3.530<.001<.00139
UCECEVL →+0.528+1.772<.001<.00139
Each partner links to its Q-omics profile. Showing the 6 strongest of 17,596 associations by consensus.

JCHAIN vs MZB1 — OV

Per-sample scatter of JCHAIN vs MZB1 in OV (Pearson r = 0.75).

Explore this scatter interactively →

Exploration