JCHAIN

Across TCGA cell cohorts, JCHAIN RNA expression is significantly associated with the go_rna of many other GO terms, with 3,662 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible JCHAIN-associated GO terms across cancer lineages are Positive regulation of respiratory burst, Neutrophil extracellular trap formation, and Neutrophil-mediated killing of fungus. Each is linked with JCHAIN in more than 13 cancer types. Because this analysis shows association rather than direction, both JCHAIN-to-partner and partner-to-JCHAIN results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Positive regulation of respiratory burst grouped by JCHAIN-low versus JCHAIN-high in LIVER.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (JCHAIN→partner) and Y-score (partner→JCHAIN) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LIVER	Positive regulation of respiratory burst →	-0.231	-1.156	.002	<.001	3	14
SKIN	Neutrophil extracellular trap formation →	+0.232	+0.782	<.001	<.001	3	7
OVARY	Neutrophil-mediated killing of fungus →	+0.137	+0.674	<.001	.004	3	7
LARGE_INTESTINE	Response to transition metal nanoparticle →	-0.146	-0.785	.006	.006	2	8
BREAST	Regulation of cilium assembly →	+0.047	+1.088	.001	.003	3	6
STOMACH	Positive regulation of telomere maintenance →	+0.066	+1.189	.001	.007	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,662 associations by consensus.

Positive regulation of respiratory burst by JCHAIN expression — LIVER

Explore this box plot interactively →