JCAD

Across TCGA patient cohorts, JCAD RNA expression is significantly associated with the protein abundance of many other proteins, with 20,024 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible JCAD-associated proteins across cancer lineages are CDH13, JCAD_S680, and JCAD_S770. Each is linked with JCAD in more than 9 cancer types. Because this analysis shows association rather than direction, both JCAD-to-partner and partner-to-JCAD results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, JCAD versus CDH13 in GBM, with a Pearson correlation of 0.40.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (JCAD→partner) and Y-score (partner→JCAD) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	CDH13 →	+0.842	+0.845	<.001	<.001	3	10
BRCA	JCAD_S680 →	+0.972	+0.922	<.001	<.001	3	10
LUAD	JCAD_S770 →	+1.099	+0.645	<.001	<.001	3	10
UCEC	JCAD_S885 →	+0.642	+0.718	<.001	<.001	3	10
UCEC	JCAD_S901 →	+0.631	+0.896	<.001	<.001	3	10
UCEC	ZYX →	+0.451	+0.753	<.001	<.001	3	9

Each partner links to its Q-omics profile. Showing the 6 strongest of 20,024 associations by consensus.

JCAD vs CDH13 — GBM

Explore this scatter interactively →