JCAD

protein abundance — cross-omics
Cross-omicsPROTEIN-MS → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, JCAD protein abundance is significantly associated with the RNA expression of many other genes, with 16,632 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible JCAD-associated genes across cancer lineages are HSPA12B, TIMP3, and PMP22. Each is linked with JCAD in more than 9 cancer types. Because this analysis shows association rather than direction, both JCAD-to-partner and partner-to-JCAD results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, JCAD versus HSPA12B in OV, with a Pearson correlation of 0.54.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (JCAD→partner) and Y-score (partner→JCAD) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
OVHSPA12B →+0.891+0.369<.001<.001310
OVTIMP3 →+1.362+0.330<.001<.00139
BRCAPMP22 →+0.898+0.342<.001<.00139
BRCARECK →+1.033+0.502<.001<.00139
UCECDDR2 →+1.341+0.761<.001<.00139
BRCAFILIP1L →+1.063+0.454<.001<.00139
Each partner links to its Q-omics profile. Showing the 6 strongest of 16,632 associations by consensus.

JCAD vs HSPA12B — OV

Per-sample scatter of JCAD vs HSPA12B in OV (Pearson r = 0.54).

Explore this scatter interactively →

Exploration