JCAD

Across TCGA cell cohorts, JCAD RNA expression is significantly associated with the go_rna of many other GO terms, with 4,175 significant associations in total. LUNG_NSCLC_LUAD shows the largest number of these associations.

The most reproducible JCAD-associated GO terms across cancer lineages are Wound healing, Positive regulation of cell-substrate adhesion, and T-helper 17 type immune response. Each is linked with JCAD in more than 9 cancer types. Because this analysis shows association rather than direction, both JCAD-to-partner and partner-to-JCAD results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Wound healing grouped by JCAD-low versus JCAD-high in LUNG_NSCLC_LUSC.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (JCAD→partner) and Y-score (partner→JCAD) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_NSCLC_LUSC	Wound healing →	+0.145	+1.949	<.001	.002	3	10
LUNG_NSCLC_LUSC	Positive regulation of cell-substrate adhesion →	+0.116	+1.533	.003	.004	2	10
LUNG_NSCLC_LUSC	T-helper 17 type immune response →	+0.168	+1.865	<.001	<.001	2	10
LUNG_NSCLC_LUSC	T-helper 17 cell differentiation →	+0.151	+1.748	.002	.001	2	10
BREAST	Positive regulation of lamellipodium assembly →	+0.128	+1.381	<.001	<.001	3	8
LUNG_NSCLC_LUSC	Morphogenesis of an epithelial sheet →	+0.175	+2.612	<.001	.001	3	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,175 associations by consensus.

Wound healing by JCAD expression — LUNG_NSCLC_LUSC

Explore this box plot interactively →