JARID2

Across TCGA patient cohorts, JARID2 mutation is significantly associated with the RNA expression of many other genes, with 2,918 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible JARID2-associated genes across cancer lineages are GINS2, ERO1A, and ZNF511. Each is linked with JARID2 in more than 2 cancer types. Because this analysis shows association rather than direction, both JARID2-to-partner and partner-to-JARID2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, GINS2 grouped by JARID2-low versus JARID2-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (JARID2→partner) and Y-score (partner→JARID2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	GINS2 →	+0.609	+1.383	<.001	<.001	3	3
STAD	ERO1A →	+1.023	+3.338	<.001	.005	3	3
STAD	ZNF511 →	+0.656	+3.338	<.001	.005	3	3
STAD	RPL34P27 →	+1.025	+3.338	<.001	.005	3	3
UCEC	COX5A →	+0.247	+1.093	.004	.005	3	3
UCEC	RWDD4 →	+0.398	+1.684	<.001	.002	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,918 associations by consensus.

GINS2 by JARID2 expression — UCEC

Explore this box plot interactively →