JARID2

Across TCGA cell cohorts, JARID2 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,563 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible JARID2-associated GO terms across cancer lineages are Facultative heterochromatin formation, Negative regulation of RNA export from nucleus, and Negative regulation of DNA-templated transcription initiation. Each is linked with JARID2 in more than 13 cancer types. Because this analysis shows association rather than direction, both JARID2-to-partner and partner-to-JARID2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Facultative heterochromatin formation grouped by JARID2-low versus JARID2-high in LUNG_NSCLC_LUSC.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (JARID2→partner) and Y-score (partner→JARID2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_NSCLC_LUSC	Facultative heterochromatin formation →	+0.103	+1.580	<.001	<.001	3	14
BONE	Negative regulation of RNA export from nucleus →	+0.155	+2.110	.002	<.001	3	14
BONE	Negative regulation of DNA-templated transcription initiation →	+0.168	+1.865	<.001	<.001	3	13
BONE	Negative regulation of transcription initiation by RNA polymerase II →	+0.168	+1.865	<.001	<.001	3	13
STOMACH	Nuclear export →	+0.114	+1.313	<.001	<.001	3	12
STOMACH	Heterochromatin organization →	+0.095	+1.388	<.001	<.001	3	12

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,563 associations by consensus.

Facultative heterochromatin formation by JARID2 expression — LUNG_NSCLC_LUSC

Explore this box plot interactively →