JARID2

Across TCGA cell cohorts, JARID2 mutation is significantly associated with the RNA expression of many other genes, with 1,620 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible JARID2-associated genes across cancer lineages are TTC19, ZSWIM7, and CEP85L. Each is linked with JARID2 in more than 2 cancer types. Because this analysis shows association rather than direction, both JARID2-to-partner and partner-to-JARID2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, TTC19 grouped by JARID2-low versus JARID2-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (JARID2→partner) and Y-score (partner→JARID2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	TTC19 →	+0.676	+2.807	<.001	<.001	3	3
BLOOD_Leukemia	ZSWIM7 →	+0.842	+3.199	.002	.007	3	3
LARGE_INTESTINE	CEP85L →	+0.459	+2.222	<.001	.001	3	3
LARGE_INTESTINE	NR2C1 →	+0.432	+2.700	<.001	.001	3	3
LARGE_INTESTINE	PPP1R3D →	-0.531	-3.459	<.001	<.001	3	3
LARGE_INTESTINE	C12orf29 →	+0.462	+2.043	.001	.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,620 associations by consensus.

TTC19 by JARID2 expression — LARGE_INTESTINE

Explore this box plot interactively →