JARID2-AS1

Across TCGA pan-cancer cohorts, JARID2-AS1 RNA differs between tumor and matched normal tissue in 11 of 18 cancer types tested, making tumor–normal expression one of JARID2-AS1’s most consistent transcriptional readouts.

The strongest signal is observed in kidney chromophobe (KICH), where JARID2-AS1 RNA is repressed in tumor relative to normal tissue. In most cancer types JARID2-AS1 is over-expressed in tumor, although a few such as KICH and KIRC show the opposite, repressed pattern.

KICH, KIRC, and LIHC are the cancer types where JARID2-AS1 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in JARID2-AS1 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
KICH	Male	All	−0.855	<.001	9	view →
KIRC	Male	II,III,IV	−0.403	<.001	8	view →
LIHC	All	All	+0.212	<.001	7	view →
BLCA	All	All	+0.463	.013	6	view →
THCA	All	All	−0.288	<.001	6	view →
COAD	All	II,III,IV	+0.301	<.001	5	view →
STAD	All	III,IV	+0.357	.038	2	view →
PRAD	All	All	+0.308	.007	2	view →
UCEC	All	All	+0.297	.033	2	view →
BRCA	Female	All	+0.164	.027	2	view →
COAD	Female	IV	−0.645	.002	1	view →
LUAD	All	All	+0.228	.042	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 12 strongest of 11 lineages.

JARID2-AS1–KICH

Open the KICH breakdown →