JAML

Across TCGA patient cohorts, JAML RNA expression is significantly associated with the protein abundance of many other proteins, with 24,972 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible JAML-associated proteins across cancer lineages are ARHGAP45, PTPN7, and RASAL3_S72. Each is linked with JAML in more than 9 cancer types. Because this analysis shows association rather than direction, both JAML-to-partner and partner-to-JAML results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, JAML versus ARHGAP45 in GBM, with a Pearson correlation of 0.74.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (JAML→partner) and Y-score (partner→JAML) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	ARHGAP45 →	+0.628	+1.011	<.001	<.001	3	10
CCRCC	PTPN7 →	+0.582	+0.796	<.001	<.001	3	10
LSCC	RASAL3_S72 →	+0.972	+1.168	<.001	<.001	3	10
OV	WIPF1 →	+0.530	+1.060	<.001	<.001	3	10
HNSC	RCSD1 →	+0.779	+1.215	<.001	<.001	3	10
HNSC	SASH3 →	+0.597	+1.122	<.001	<.001	3	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 24,972 associations by consensus.

JAML vs ARHGAP45 — GBM

Explore this scatter interactively →