JAML

Across TCGA cell cohorts, JAML RNA expression is significantly associated with the go_rna of many other GO terms, with 1,876 significant associations in total. LIVER shows the largest number of these associations.

The most reproducible JAML-associated GO terms across cancer lineages are Striatal medium spiny neuron differentiation, Regulation of release of cytochrome c from mitochondria, and Regulation of cytotoxic T cell degranulation. Each is linked with JAML in more than 6 cancer types. Because this analysis shows association rather than direction, both JAML-to-partner and partner-to-JAML results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Striatal medium spiny neuron differentiation grouped by JAML-low versus JAML-high in LIVER.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (JAML→partner) and Y-score (partner→JAML) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LIVER	Striatal medium spiny neuron differentiation →	-1.127	-1.690	.001	.006	2	7
SKIN	Regulation of release of cytochrome c from mitochondria →	-0.087	-0.060	.006	.006	3	6
LIVER	Regulation of cytotoxic T cell degranulation →	+1.778	+2.033	<.001	<.001	3	6
LIVER	Negative regulation of cytotoxic T cell degranulation →	+1.778	+2.033	<.001	<.001	3	6
LIVER	Negative regulation of T-helper cell differentiation →	-0.103	-1.858	.003	.002	3	6
LIVER	Organic cation transport →	+0.128	+2.488	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,876 associations by consensus.

Striatal medium spiny neuron differentiation by JAML expression — LIVER

Explore this box plot interactively →