JAM3

Across TCGA patient cohorts, JAM3 RNA expression is significantly associated with the protein abundance of many other proteins, with 23,083 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible JAM3-associated proteins across cancer lineages are SORBS3, MAP1A, and TTC7B. Each is linked with JAM3 in more than 9 cancer types. Because this analysis shows association rather than direction, both JAM3-to-partner and partner-to-JAM3 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, JAM3 versus SORBS3 in UCEC, with a Pearson correlation of 0.72.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (JAM3→partner) and Y-score (partner→JAM3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	SORBS3 →	+0.596	+0.795	<.001	<.001	3	10
HNSC	MAP1A →	+0.601	+0.657	<.001	<.001	3	10
COAD	TTC7B →	+0.488	+0.726	<.001	.004	3	10
UCEC	ZYX →	+0.565	+0.829	<.001	<.001	3	9
UCEC	RSU1 →	+0.578	+0.924	<.001	<.001	3	9
UCEC	SARM1 →	+0.568	+0.955	<.001	<.001	3	9

Each partner links to its Q-omics profile. Showing the 6 strongest of 23,083 associations by consensus.

JAM3 vs SORBS3 — UCEC

Explore this scatter interactively →