JAM3

Across TCGA patient cohorts, JAM3 protein abundance is significantly associated with the RNA expression of many other genes, with 12,606 significant associations in total. CCRCC shows the largest number of these associations.

The most reproducible JAM3-associated genes across cancer lineages are TAL1, LMOD1, and ACTA2-AS1. Each is linked with JAM3 in more than 7 cancer types. Because this analysis shows association rather than direction, both JAM3-to-partner and partner-to-JAM3 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, JAM3 versus TAL1 in CCRCC, with a Pearson correlation of 0.77.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (JAM3→partner) and Y-score (partner→JAM3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CCRCC	TAL1 →	+1.182	+0.636	<.001	<.001	3	8
COAD	LMOD1 →	+1.453	+0.388	<.001	<.001	3	8
UCEC	ACTA2-AS1 →	+1.039	+0.430	<.001	<.001	3	8
OV	DACT3 →	+0.934	+0.747	<.001	<.001	3	8
CCRCC	PTH1R →	+1.120	+0.333	<.001	<.001	3	8
OV	CNRIP1 →	+0.889	+0.578	<.001	<.001	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 12,606 associations by consensus.

JAM3 vs TAL1 — CCRCC

Explore this scatter interactively →