JAM3

Across TCGA cell cohorts, JAM3 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,091 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible JAM3-associated GO terms across cancer lineages are Microtubule-based transport, Positive regulation of sodium ion transport, and Nuclear RNA surveillance. Each is linked with JAM3 in more than 11 cancer types. Because this analysis shows association rather than direction, both JAM3-to-partner and partner-to-JAM3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Microtubule-based transport grouped by JAM3-low versus JAM3-high in LUNG_NSCLC_LUSC.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (JAM3→partner) and Y-score (partner→JAM3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_NSCLC_LUSC	Microtubule-based transport →	+0.049	+1.945	.003	.007	2	12
LUNG_NSCLC_LUSC	Positive regulation of sodium ion transport →	-0.204	-2.038	.005	.009	3	11
OVARY	Nuclear RNA surveillance →	+0.085	+2.724	<.001	<.001	2	12
STOMACH	Negative regulation of integrin activation →	+1.080	+2.871	<.001	<.001	2	12
URINARY_TRACT	Potassium ion import across plasma membrane →	-0.215	-2.041	<.001	<.001	3	11
PANCREAS	DNA biosynthetic process →	+0.072	+1.259	<.001	.001	2	11

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,091 associations by consensus.

Microtubule-based transport by JAM3 expression — LUNG_NSCLC_LUSC

Explore this box plot interactively →