JAKMIP3

mutation — cross-omics
Cross-omicsMUTATION → PROTEIN-RPPAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, JAKMIP3 mutation is significantly associated with the total protein of many other genes, with 43 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible JAKMIP3-associated genes across cancer lineages are ASNS, ATM, and Caspase-7-cleavedD198. Each is linked with JAKMIP3 in more than 2 cancer types. Because this analysis shows association rather than direction, both JAKMIP3-to-partner and partner-to-JAKMIP3 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (JAKMIP3→partner) and Y-score (partner→JAKMIP3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
UCECASNS →+0.341+1.415.003.04333
UCECATM →-0.566-2.321<.001<.00133
COADCaspase-7-cleavedD198 →+1.436+3.008<.001.01933
UCECGSK3-a-b →+0.097+1.584.026.03432
UCECJNK_pT183_Y185 →-0.195-1.986<.001<.00132
UCECMEK1 →+0.305+2.000.010<.00132
Each partner links to its Q-omics profile. Showing the 6 strongest of 43 associations by consensus.

Exploration