Across TCGA cell cohorts, JAKMIP3 mutation is significantly associated with the RNA expression of many other genes, with 125 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible JAKMIP3-associated genes across cancer lineages are KRTAP5-6, OR10A2, and ASCL3. Each is linked with JAKMIP3 in more than 1 cancer types. Because this analysis shows association rather than direction, both JAKMIP3-to-partner and partner-to-JAKMIP3 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (JAKMIP3→partner) and Y-score (partner→JAKMIP3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OVARY	KRTAP5-6 →	+0.124	+4.022	<.001	.001	3	2
OVARY	OR10A2 →	+0.030	+3.987	<.001	<.001	3	1
OVARY	ASCL3 →	+0.229	+3.722	<.001	.002	3	1
OVARY	C3orf22 →	+0.036	+4.523	<.001	<.001	3	1
OVARY	SPEM1 →	+0.091	+3.510	.004	.005	3	1
OVARY	TMEM89 →	+0.102	+3.378	<.001	.006	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 125 associations by consensus.

Exploration

JAKMIP3 survival (RNA) · tumor vs normal (RNA) · all JAKMIP3 data types