JAKMIP2

Across TCGA patient cohorts, JAKMIP2 protein abundance is significantly associated with the RNA expression of many other genes, with 6,275 significant associations in total. GBM shows the largest number of these associations.

The most reproducible JAKMIP2-associated genes across cancer lineages are SPECC1L, SNRPD3, and GGT1. Each is linked with JAKMIP2 in more than 1 cancer types. Because this analysis shows association rather than direction, both JAKMIP2-to-partner and partner-to-JAKMIP2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, JAKMIP2 versus SPECC1L in GBM, with a Pearson correlation of 0.34.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (JAKMIP2→partner) and Y-score (partner→JAKMIP2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	SPECC1L →	+0.287	+0.287	.002	<.001	3	1
GBM	SNRPD3 →	+0.403	+0.294	<.001	<.001	3	1
GBM	GGT1 →	+0.161	+0.213	<.001	.001	3	1
GBM	PRODH →	+0.799	+0.262	<.001	<.001	3	1
GBM	CYTH4 →	-0.934	-0.400	<.001	<.001	3	1
GBM	SEZ6L →	+1.487	+0.331	<.001	<.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,275 associations by consensus.

JAKMIP2 vs SPECC1L — GBM

Explore this scatter interactively →