JAKMIP2

Across TCGA cell cohorts, JAKMIP2 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,737 significant associations in total. BONE shows the largest number of these associations.

The most reproducible JAKMIP2-associated GO terms across cancer lineages are Proton motive force-driven mitochondrial ATP synthesis, Ribonucleoside triphosphate biosynthetic process, and Proton motive force-driven ATP synthesis. Each is linked with JAKMIP2 in more than 10 cancer types. Because this analysis shows association rather than direction, both JAKMIP2-to-partner and partner-to-JAKMIP2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Proton motive force-driven mitochondrial ATP synthesis grouped by JAKMIP2-low versus JAKMIP2-high in LUNG_SCLC.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (JAKMIP2→partner) and Y-score (partner→JAKMIP2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_SCLC	Proton motive force-driven mitochondrial ATP synthesis →	+0.086	+1.712	.001	.001	3	11
LUNG_NSCLC_LUSC	Ribonucleoside triphosphate biosynthetic process →	+0.089	+1.091	<.001	.003	3	10
LUNG_SCLC	Proton motive force-driven ATP synthesis →	+0.087	+1.642	.001	.001	3	10
LUNG_SCLC	Oxidative phosphorylation →	+0.089	+1.927	<.001	<.001	3	10
LUNG_NSCLC_LUSC	Nucleoside triphosphate biosynthetic process →	+0.076	+1.018	.001	.007	2	10
LUNG_NSCLC_LUSC	Purine nucleoside triphosphate biosynthetic process →	+0.091	+0.969	<.001	.004	3	9

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,737 associations by consensus.

Proton motive force-driven mitochondrial ATP synthesis by JAKMIP2 expression — LUNG_SCLC

Explore this box plot interactively →