JAKMIP1

Across TCGA cell cohorts, JAKMIP1 mutation is significantly associated with the RNA expression of many other genes, with 1,484 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible JAKMIP1-associated genes across cancer lineages are FBXO6, WDR89, and METTL14. Each is linked with JAKMIP1 in more than 1 cancer types. Because this analysis shows association rather than direction, both JAKMIP1-to-partner and partner-to-JAKMIP1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, FBXO6 grouped by JAKMIP1-low versus JAKMIP1-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (JAKMIP1→partner) and Y-score (partner→JAKMIP1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	FBXO6 →	+1.112	+3.169	<.001	.006	3	2
LUNG_NSCLC_LUAD	WDR89 →	+0.442	+2.495	.003	.006	3	2
LARGE_INTESTINE	METTL14 →	+0.543	+2.265	.001	.001	3	2
LARGE_INTESTINE	RPL7L1 →	+0.453	+3.459	.006	.001	3	2
LARGE_INTESTINE	AASDH →	+0.649	+2.949	<.001	<.001	3	2
LARGE_INTESTINE	CRLF3 →	+0.432	+2.265	.008	.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,484 associations by consensus.

FBXO6 by JAKMIP1 expression — LARGE_INTESTINE

Explore this box plot interactively →