JAK2

RNA expression — cross-omics
Cross-omicsRNA → PROTEIN-MSPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, JAK2 RNA expression is significantly associated with the protein abundance of many other proteins, with 14,687 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible JAK2-associated proteins across cancer lineages are EVL, RASAL3, and CORO1A. Each is linked with JAK2 in more than 9 cancer types. Because this analysis shows association rather than direction, both JAK2-to-partner and partner-to-JAK2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, JAK2 versus EVL in HNSC, with a Pearson correlation of 0.58.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (JAK2→partner) and Y-score (partner→JAK2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner proteinX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
HNSCEVL →+0.679+0.829<.001<.001310
OVRASAL3 →+0.570+0.987<.001<.00139
GBMCORO1A →+0.665+0.744<.001<.00139
GBMGIMAP4 →+0.663+0.607<.001<.00139
HNSCGIMAP7 →+0.632+0.843<.001<.00139
HNSCUBA7 →+0.468+1.013<.001<.00139
Each partner links to its Q-omics profile. Showing the 6 strongest of 14,687 associations by consensus.

JAK2 vs EVL — HNSC

Per-sample scatter of JAK2 vs EVL in HNSC (Pearson r = 0.58).

Explore this scatter interactively →

Exploration