JAGN1

Across TCGA cell cohorts, JAGN1 RNA expression is significantly associated with the go_rna of many other GO terms, with 2,596 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible JAGN1-associated GO terms across cancer lineages are Granulocyte colony-stimulating factor signaling pathway, Neutrophil differentiation, and Mitochondrial disulfide relay system. Each is linked with JAGN1 in more than 18 cancer types. Because this analysis shows association rather than direction, both JAGN1-to-partner and partner-to-JAGN1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Granulocyte colony-stimulating factor signaling pathway grouped by JAGN1-low versus JAGN1-high in PANCREAS.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (JAGN1→partner) and Y-score (partner→JAGN1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
PANCREAS	Granulocyte colony-stimulating factor signaling pathway →	+0.274	+0.680	<.001	<.001	3	19
LUNG_NSCLC_LUSC	Neutrophil differentiation →	+0.274	+1.167	.001	.001	3	17
OESOPHAGUS	Mitochondrial disulfide relay system →	+0.144	+0.733	.001	.001	3	14
LUNG_NSCLC_LUSC	Protein import into mitochondrial intermembrane space →	+0.153	+0.775	.001	.006	3	13
UPPER_AERODIGESTIVE_TRACT	tRNA-type intron splice site recognition and cleavage →	+0.113	+0.965	.001	.007	3	12
LARGE_INTESTINE	Mitochondrial translation →	+0.063	+0.582	<.001	<.001	3	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,596 associations by consensus.

Granulocyte colony-stimulating factor signaling pathway by JAGN1 expression — PANCREAS

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