JAG1

Across TCGA patient cohorts, JAG1 RNA expression is significantly associated with the protein abundance of many other proteins, with 15,244 significant associations in total. CCRCC shows the largest number of these associations.

The most reproducible JAG1-associated proteins across cancer lineages are MCC, ME2, and ACTN4. Each is linked with JAG1 in more than 4 cancer types. Because this analysis shows association rather than direction, both JAG1-to-partner and partner-to-JAG1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, JAG1 versus MCC in GBM, with a Pearson correlation of 0.47.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (JAG1→partner) and Y-score (partner→JAG1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	MCC →	+0.479	+1.330	<.001	<.001	3	5
UCEC	ME2 →	-0.399	-0.732	<.001	<.001	3	5
CCRCC	ACTN4 →	+0.272	+0.948	<.001	<.001	3	5
UCEC	CD109 →	+0.657	+0.591	.002	<.001	3	5
GBM	FGD3_S128 →	-0.543	-0.790	<.001	<.001	3	5
OV	HSPD1 →	-0.658	-1.390	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 15,244 associations by consensus.

JAG1 vs MCC — GBM

Explore this scatter interactively →