JADE2

Across TCGA patient cohorts, JADE2 RNA expression is significantly associated with the protein abundance of many other proteins, with 14,980 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible JADE2-associated proteins across cancer lineages are MAT2B, MAT2A, and HINT1. Each is linked with JADE2 in more than 6 cancer types. Because this analysis shows association rather than direction, both JADE2-to-partner and partner-to-JADE2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, JADE2 versus MAT2B in OV, with a Pearson correlation of 0.31.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (JADE2→partner) and Y-score (partner→JADE2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	MAT2B →	+0.196	+0.657	.001	.009	3	7
BRCA	MAT2A →	+0.193	+0.678	<.001	.001	3	5
UCEC	HINT1 →	+0.272	+0.592	.002	.001	3	5
BRCA	PHF3_S1133 →	-0.338	-0.524	<.001	.002	3	4
OV	MAPK9 →	+0.435	+1.321	<.001	<.001	3	4
LUAD	RACGAP1 →	-0.528	-0.379	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 14,980 associations by consensus.

JADE2 vs MAT2B — OV

Explore this scatter interactively →