Across TCGA patient cohorts, IZUMO3 RNA expression is significantly associated with the go_rna of many other GO terms, with 6,462 significant associations in total. STAD shows the largest number of these associations.

The most reproducible IZUMO3-associated GO terms across cancer lineages are Mitochondrial gene expression, Protein N-linked glycosylation, and Positive regulation of DNA metabolic process. Each is linked with IZUMO3 in more than 9 cancer types. Because this analysis shows association rather than direction, both IZUMO3-to-partner and partner-to-IZUMO3 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (IZUMO3→partner) and Y-score (partner→IZUMO3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STAD	Mitochondrial gene expression →	+0.096	+0.224	<.001	<.001	3	10
STAD	Protein N-linked glycosylation →	+0.076	+0.182	<.001	<.001	3	10
STAD	Positive regulation of DNA metabolic process →	+0.083	+0.212	<.001	<.001	3	10
STAD	Chaperone-mediated protein folding →	+0.091	+0.192	<.001	<.001	3	10
STAD	Regulation of exocytosis →	+0.057	+0.220	<.001	<.001	3	10
STAD	Regulation of endosome size →	+0.066	+0.182	<.001	<.001	3	9

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,462 associations by consensus.

Exploration

IZUMO3 survival (RNA) · tumor vs normal (RNA) · all IZUMO3 data types