IWS1

Across TCGA patient cohorts, IWS1 RNA expression is significantly associated with the protein abundance of many other proteins, with 15,564 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible IWS1-associated proteins across cancer lineages are TSN, SF3A1, and TRRAP. Each is linked with IWS1 in more than 5 cancer types. Because this analysis shows association rather than direction, both IWS1-to-partner and partner-to-IWS1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, IWS1 versus TSN in LUAD, with a Pearson correlation of 0.40.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (IWS1→partner) and Y-score (partner→IWS1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUAD	TSN →	+0.277	+0.472	<.001	<.001	3	6
GBM	SF3A1 →	+0.180	+0.194	<.001	<.001	3	5
LSCC	TRRAP →	+0.263	+0.425	<.001	<.001	3	5
LSCC	ILKAP →	+0.324	+0.482	<.001	<.001	3	5
LSCC	SUPT6H →	+0.254	+0.414	<.001	<.001	3	5
LSCC	GTF3C2 →	+0.273	+0.313	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 15,564 associations by consensus.

IWS1 vs TSN — LUAD

Explore this scatter interactively →