IWS1

Across TCGA cell cohorts, IWS1 RNA expression is significantly associated with the RNA expression of many other genes, with 11,414 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible IWS1-associated genes across cancer lineages are ERCC3, SMPD4, and WDR33. Each is linked with IWS1 in more than 19 cancer types. Because this analysis shows association rather than direction, both IWS1-to-partner and partner-to-IWS1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, IWS1 versus ERCC3 in OESOPHAGUS, with a Pearson correlation of 0.72.

RNA expression associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (IWS1→partner) and Y-score (partner→IWS1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OESOPHAGUS	ERCC3 →	+1.061	+0.865	.001	.002	3	20
BLOOD_Myeloma	SMPD4 →	+0.941	+0.650	<.001	<.001	3	19
LUNG_NSCLC_LUSC	WDR33 →	+0.869	+0.728	<.001	<.001	3	19
BONE	RBM12 →	+1.054	+0.737	<.001	<.001	3	18
URINARY_TRACT	SAP130 →	+0.808	+0.635	<.001	<.001	3	18
BONE	AMMECR1L →	+0.914	+0.924	<.001	<.001	3	18

Each partner links to its Q-omics profile. Showing the 6 strongest of 11,414 associations by consensus.

IWS1 vs ERCC3 — OESOPHAGUS

Explore this scatter interactively →