IWS1

Across TCGA cell cohorts, IWS1 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,948 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible IWS1-associated GO terms across cancer lineages are Nuclear export, RNA export from nucleus, and Replication fork processing. Each is linked with IWS1 in more than 16 cancer types. Because this analysis shows association rather than direction, both IWS1-to-partner and partner-to-IWS1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Nuclear export grouped by IWS1-low versus IWS1-high in UPPER_AERODIGESTIVE_TRACT.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (IWS1→partner) and Y-score (partner→IWS1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UPPER_AERODIGESTIVE_TRACT	Nuclear export →	+0.087	+0.756	.001	<.001	3	17
UPPER_AERODIGESTIVE_TRACT	RNA export from nucleus →	+0.120	+0.661	<.001	<.001	3	17
BLOOD_Myeloma	Replication fork processing →	+0.087	+0.601	.002	.001	3	16
BONE	Nucleic acid transport →	+0.103	+0.522	.001	.003	3	16
BONE	RNA transport →	+0.103	+0.522	.001	.003	3	16
BONE	Positive regulation of mRNA processing →	+0.101	+0.573	.002	.001	3	16

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,948 associations by consensus.

Nuclear export by IWS1 expression — UPPER_AERODIGESTIVE_TRACT

Explore this box plot interactively →