IVNS1ABP

Across TCGA pan-cancer cohorts, IVNS1ABP mass-spec protein is linked to patient survival in 5 of 34 cancer types, making it a survival-associated IVNS1ABP data layer compared with 20 for mass-spec protein and 6 for mutation status.

The strongest signal is observed in lung adenocarcinoma (LUAD), where higher IVNS1ABP mass-spec protein is associated with worse disease-free survival. In most high-consensus cancer types, elevated IVNS1ABP expression acts as an unfavorable survival marker, although some lineages such as HNSC and UCEC show a favorable association.

LUAD, COAD, and HNSC are the cancer types where IVNS1ABP mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
LUAD	DFS	Quartile	All	0.416	0.745	.001	36	view →
COAD	DFS	Median	All	0.926	1.000	.023	24	view →
HNSC	DFS	Median	III,IV	0.882	0.691	.008	12	view →
PDAC	DFS	Quartile	II,III,IV	0.385	0.710	.021	8	view →
UCEC	OS	Tertile	All	1.000	0.888	.036	6	view →

Pink = unfavorable, green = favorable. Showing the 5 strongest of 5 lineages.

IVNS1ABP–LUAD (DFS)

Open the LUAD breakdown →