Across TCGA patient cohorts, ITSN2 RNA expression is significantly associated with the protein abundance of many other proteins, with 9,011 significant associations in total. GBM shows the largest number of these associations.

The most reproducible ITSN2-associated proteins across cancer lineages are ITSN2_S889, TBRG4, and TTI2. Each is linked with ITSN2 in more than 4 cancer types. Because this analysis shows association rather than direction, both ITSN2-to-partner and partner-to-ITSN2 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (ITSN2→partner) and Y-score (partner→ITSN2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
PDAC	ITSN2_S889 →	+0.632	+0.321	<.001	<.001	3	5
PDAC	TBRG4 →	-0.516	-0.314	<.001	<.001	3	4
CCRCC	TTI2 →	-0.291	-0.207	<.001	<.001	3	4
CCRCC	SRP68 →	-0.159	-0.213	<.001	<.001	3	4
PDAC	LYSMD2 →	+0.458	+0.305	.009	<.001	3	4
PDAC	DDX28 →	-0.355	-0.255	<.001	.003	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 9,011 associations by consensus.

Exploration

ITSN2 survival (RNA) · tumor vs normal (RNA) · all ITSN2 data types