Across TCGA patient cohorts, ITSN2 protein abundance is significantly associated with the RNA expression of many other genes, with 15,769 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible ITSN2-associated genes across cancer lineages are CTSS, SIRPB1, and PTAFR. Each is linked with ITSN2 in more than 6 cancer types. Because this analysis shows association rather than direction, both ITSN2-to-partner and partner-to-ITSN2 results are reported.

Each partner links to its own Q-omics profile.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ITSN2→partner) and Y-score (partner→ITSN2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	CTSS →	+1.104	+0.301	<.001	<.001	3	7
UCEC	SIRPB1 →	+0.641	+0.279	.004	<.001	3	6
OV	PTAFR →	+1.080	+0.304	.001	<.001	3	6
GBM	ARHGAP30 →	+0.867	+0.281	<.001	<.001	3	6
GBM	CSF2RA →	+0.878	+0.234	<.001	<.001	3	6
OV	DAPP1 →	+1.195	+0.374	<.001	<.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 15,769 associations by consensus.

Exploration

ITSN2 survival (RNA) · tumor vs normal (RNA) · all ITSN2 data types