Across TCGA patient cohorts, ITSN1 RNA expression is significantly associated with the protein abundance of many other proteins, with 17,295 significant associations in total. PDAC shows the largest number of these associations.

The most reproducible ITSN1-associated proteins across cancer lineages are DPYSL3, RPL6, and SEPTIN11. Each is linked with ITSN1 in more than 6 cancer types. Because this analysis shows association rather than direction, both ITSN1-to-partner and partner-to-ITSN1 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (ITSN1→partner) and Y-score (partner→ITSN1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
COAD	DPYSL3 →	+0.609	+0.297	<.001	<.001	3	7
GBM	RPL6 →	-0.481	-0.450	.004	<.001	3	6
LSCC	SEPTIN11 →	+0.308	+0.377	<.001	<.001	3	6
BRCA	RPL5 →	-0.211	-0.514	<.001	<.001	3	6
LUAD	CLPX →	-0.233	-0.340	.001	<.001	3	6
BRCA	COL1A1 →	+0.841	+0.612	<.001	<.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 17,295 associations by consensus.

Exploration

ITSN1 survival (RNA) · tumor vs normal (RNA) · all ITSN1 data types