Across TCGA patient cohorts, ITSN1 protein abundance is significantly associated with the RNA expression of many other genes, with 17,053 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible ITSN1-associated genes across cancer lineages are HTR2A, SCN2B, and ADH1B. Each is linked with ITSN1 in more than 8 cancer types. Because this analysis shows association rather than direction, both ITSN1-to-partner and partner-to-ITSN1 results are reported.

Each partner links to its own Q-omics profile.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ITSN1→partner) and Y-score (partner→ITSN1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	HTR2A →	+0.958	+0.295	<.001	<.001	3	9
GBM	SCN2B →	+1.143	+0.273	<.001	<.001	3	9
BRCA	ADH1B →	+2.094	+0.365	<.001	<.001	3	9
UCEC	SRPX →	+1.227	+0.283	<.001	<.001	3	8
BRCA	MEIS3 →	+1.183	+0.305	<.001	<.001	3	8
CCRCC	AEBP1 →	+1.246	+0.214	.009	.003	3	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 17,053 associations by consensus.

Exploration

ITSN1 survival (RNA) · tumor vs normal (RNA) · all ITSN1 data types