Across TCGA patient cohorts, ITSN1 mutation is significantly associated with the RNA expression of many other genes, with 5,034 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ITSN1-associated genes across cancer lineages are RNA5SP436, PSMC1P3, and TUBB4BP8. Each is linked with ITSN1 in more than 2 cancer types. Because this analysis shows association rather than direction, both ITSN1-to-partner and partner-to-ITSN1 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ITSN1→partner) and Y-score (partner→ITSN1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUSC	RNA5SP436 →	+0.404	+3.932	<.001	.009	3	3
READ	PSMC1P3 →	+0.126	+4.022	<.001	.002	3	3
STAD	TUBB4BP8 →	+0.270	+4.564	<.001	<.001	3	3
UCEC	LINC02438 →	+0.570	+2.000	<.001	<.001	3	3
SKCM	RPS3AP11 →	+0.069	+2.078	.004	<.001	3	3
UCEC	OIP5 →	+0.636	+1.862	<.001	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,034 associations by consensus.

Exploration

ITSN1 survival (RNA) · tumor vs normal (RNA) · all ITSN1 data types