Across TCGA cell cohorts, ITSN1 mutation is significantly associated with the RNA expression of many other genes, with 456 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible ITSN1-associated genes across cancer lineages are TXNL4A, SLC30A9, and CTSS. Each is linked with ITSN1 in more than 1 cancer types. Because this analysis shows association rather than direction, both ITSN1-to-partner and partner-to-ITSN1 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ITSN1→partner) and Y-score (partner→ITSN1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	TXNL4A →	+0.763	+3.743	<.001	<.001	3	2
LARGE_INTESTINE	SLC30A9 →	+0.493	+2.628	<.001	.002	3	2
LARGE_INTESTINE	CTSS →	-1.950	-2.541	.003	.005	3	2
LARGE_INTESTINE	H2AZ1 →	+0.656	+3.389	<.001	.001	3	2
LARGE_INTESTINE	BCL2 →	+0.678	+2.628	.006	.002	3	2
LARGE_INTESTINE	PARD6G →	+1.081	+3.743	<.001	<.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 456 associations by consensus.

Exploration

ITSN1 survival (RNA) · tumor vs normal (RNA) · all ITSN1 data types