Across TCGA patient cohorts, ITPRIPL2 RNA expression is significantly associated with the protein abundance of many other proteins, with 16,548 significant associations in total. GBM shows the largest number of these associations.

The most reproducible ITPRIPL2-associated proteins across cancer lineages are RCN3, CNN2, and SPARC. Each is linked with ITPRIPL2 in more than 6 cancer types. Because this analysis shows association rather than direction, both ITPRIPL2-to-partner and partner-to-ITPRIPL2 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (ITPRIPL2→partner) and Y-score (partner→ITPRIPL2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	RCN3 →	+0.721	+0.458	.001	.002	3	7
GBM	CNN2 →	+0.917	+0.557	<.001	<.001	3	7
OV	SPARC →	+0.766	+0.919	<.001	<.001	3	6
OV	FN1 →	+0.690	+0.541	.002	.007	3	6
GBM	COL3A1 →	+1.037	+0.536	<.001	.001	3	6
COAD	CTHRC1 →	+1.003	+0.655	<.001	<.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 16,548 associations by consensus.

Exploration

ITPRIPL2 survival (RNA) · tumor vs normal (RNA) · all ITPRIPL2 data types