ITPRIPL1

mutation — cross-omics
Cross-omicsMUTATION → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, ITPRIPL1 mutation is significantly associated with the RNA expression of many other genes, with 1,948 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ITPRIPL1-associated genes across cancer lineages are VN1R85P, MIR6765, and RNA5SP411. Each is linked with ITPRIPL1 in more than 1 cancer types. Because this analysis shows association rather than direction, both ITPRIPL1-to-partner and partner-to-ITPRIPL1 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ITPRIPL1→partner) and Y-score (partner→ITPRIPL1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
BLCAVN1R85P →+0.924+3.681.002.00732
BLCAMIR6765 →+0.292+4.814<.001.00332
UCECRNA5SP411 →+0.751+1.628.001.00532
COADCYCSP41 →+0.440+5.136<.001.00232
READRN7SL865P →+0.165+6.257<.001.00132
READCOX6CP3 →+0.194+5.421.003.00532
Each partner links to its Q-omics profile. Showing the 6 strongest of 1,948 associations by consensus.

Exploration