ITPRID1

Across TCGA pan-cancer cohorts, ITPRID1 Mutation is linked to patient survival in 5 of 34 cancer types, making it a survival-associated ITPRID1 data layer compared with 19 for mass-spec protein.

The strongest signal is observed in cervical squamous cell carcinoma and endocervical adenocarcinoma (CESC), where higher ITPRID1 Mutation is associated with worse overall survival. In most high-consensus cancer types, elevated ITPRID1 expression acts as an unfavorable survival marker, although some lineages such as UCEC show a favorable association.

CESC, UCEC, and COAD are the cancer types where ITPRID1 Mutation most reproducibly stratifies survival.

Mutation survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
CESC	OS	Median	II,III,IV	0.121	0.829	<.001	36	view →
UCEC	DFS	Median	All	0.982	0.889	.009	32	view →
COAD	OS	Median	All	0.487	0.877	.002	12	view →
ESCA	OS	Median	II,III,IV	0.216	0.702	.014	6	view →
BLCA	OS	Median	III,IV	0.069	0.582	<.001	6	view →

Pink = unfavorable, green = favorable. Showing the 5 strongest of 5 lineages.

ITPRID1–CESC (OS)

Open the CESC breakdown →