ITPRID1

Across TCGA patient cohorts, ITPRID1 mutation is significantly associated with the RNA expression of many other genes, with 4,406 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ITPRID1-associated genes across cancer lineages are UQCRH, ZNHIT3, and KCNIP2-AS1. Each is linked with ITPRID1 in more than 3 cancer types. Because this analysis shows association rather than direction, both ITPRID1-to-partner and partner-to-ITPRID1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, UQCRH grouped by ITPRID1-low versus ITPRID1-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ITPRID1→partner) and Y-score (partner→ITPRID1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	UQCRH →	+0.630	+1.506	.005	.002	3	4
UCEC	ZNHIT3 →	+0.390	+1.928	<.001	<.001	3	4
UCEC	KCNIP2-AS1 →	+0.317	+1.741	<.001	<.001	3	4
UCEC	CDKN3 →	+0.584	+2.145	<.001	<.001	3	4
UCEC	OIP5 →	+0.694	+1.709	<.001	<.001	3	4
SKCM	DNAJC8 →	+0.371	+2.925	.002	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,406 associations by consensus.

UQCRH by ITPRID1 expression — UCEC

Explore this box plot interactively →