ITPRID1

Across TCGA cell cohorts, ITPRID1 mutation is significantly associated with the RNA expression of many other genes, with 250 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible ITPRID1-associated genes across cancer lineages are FBXO25, CDC40, and MMP20. Each is linked with ITPRID1 in more than 1 cancer types. Because this analysis shows association rather than direction, both ITPRID1-to-partner and partner-to-ITPRID1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, FBXO25 grouped by ITPRID1-low versus ITPRID1-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ITPRID1→partner) and Y-score (partner→ITPRID1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	FBXO25 →	+0.880	+3.321	<.001	.002	3	2
LARGE_INTESTINE	CDC40 →	+0.506	+3.169	.007	.009	3	2
BLOOD_Leukemia	MMP20 →	+0.061	+4.705	<.001	.003	3	2
BLOOD_Leukemia	CFHR2 →	+0.296	+4.539	<.001	.007	3	2
PANCREAS	XPNPEP2 →	+0.040	+4.011	<.001	.009	3	1
PANCREAS	OR10Q1 →	+0.025	+4.614	<.001	.004	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 250 associations by consensus.

FBXO25 by ITPRID1 expression — LARGE_INTESTINE

Explore this box plot interactively →