ITPR3

Across TCGA patient cohorts, ITPR3 RNA expression is significantly associated with the protein abundance of many other proteins, with 11,065 significant associations in total. GBM shows the largest number of these associations.

The most reproducible ITPR3-associated proteins across cancer lineages are ITPR3_S2670, SRPK1, and SMC2. Each is linked with ITPR3 in more than 5 cancer types. Because this analysis shows association rather than direction, both ITPR3-to-partner and partner-to-ITPR3 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, ITPR3 versus ITPR3_S2670 in LUAD, with a Pearson correlation of 0.35.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (ITPR3→partner) and Y-score (partner→ITPR3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUAD	ITPR3_S2670 →	+0.764	+0.681	<.001	<.001	3	6
PDAC	SRPK1 →	+0.365	+0.709	<.001	<.001	3	5
LSCC	SMC2 →	+0.323	+0.501	.001	<.001	3	4
PDAC	HARS2_S67 →	+0.642	+0.553	.002	.008	3	4
PDAC	WRNIP1 →	+0.308	+0.510	<.001	.004	3	4
LSCC	XPO5 →	+0.361	+0.521	.001	<.001	2	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 11,065 associations by consensus.

ITPR3 vs ITPR3_S2670 — LUAD

Explore this scatter interactively →