ITPR2

Across TCGA cell cohorts, ITPR2 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,201 significant associations in total. CNS shows the largest number of these associations.

The most reproducible ITPR2-associated GO terms across cancer lineages are Cytosolic transport, Retrograde transport, endosome to Golgi, and Vesicle-mediated transport to the plasma membrane. Each is linked with ITPR2 in more than 12 cancer types. Because this analysis shows association rather than direction, both ITPR2-to-partner and partner-to-ITPR2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Cytosolic transport grouped by ITPR2-low versus ITPR2-high in OVARY.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (ITPR2→partner) and Y-score (partner→ITPR2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OVARY	Cytosolic transport →	+0.061	+1.135	<.001	<.001	3	13
UPPER_AERODIGESTIVE_TRACT	Retrograde transport, endosome to Golgi →	+0.092	+1.403	<.001	.001	3	12
OESOPHAGUS	Vesicle-mediated transport to the plasma membrane →	+0.072	+1.039	<.001	.008	2	12
UPPER_AERODIGESTIVE_TRACT	Regulation of organelle assembly →	+0.049	+1.220	<.001	.006	3	10
UPPER_AERODIGESTIVE_TRACT	Cellular response to insulin stimulus →	+0.060	+1.153	<.001	.002	3	10
CNS	Cortical microtubule organization →	+0.110	+0.804	.005	.006	2	11

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,201 associations by consensus.

Cytosolic transport by ITPR2 expression — OVARY

Explore this box plot interactively →