ITPKC

RNA expression — cross-omics
Cross-omicsRNA → PROTEIN-MSPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, ITPKC RNA expression is significantly associated with the protein abundance of many other proteins, with 11,982 significant associations in total. GBM shows the largest number of these associations.

The most reproducible ITPKC-associated proteins across cancer lineages are ZFP36_S60, BLVRB, and ZFP36_S186. Each is linked with ITPKC in more than 4 cancer types. Because this analysis shows association rather than direction, both ITPKC-to-partner and partner-to-ITPKC results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, ITPKC versus ZFP36_S60 in LSCC, with a Pearson correlation of 0.48.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (ITPKC→partner) and Y-score (partner→ITPKC) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner proteinX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
LSCCZFP36_S60 →+1.070+1.037<.001<.00135
GBMBLVRB →+0.529+0.531<.001<.00135
OVZFP36_S186 →+1.151+0.749<.001.00134
GBMRCC2_S51 →-0.729-0.954<.001<.00134
GBMCEBPD →+0.443+0.518<.001<.00134
GBMSVIL →+0.394+0.555<.001<.00133
Each partner links to its Q-omics profile. Showing the 6 strongest of 11,982 associations by consensus.

ITPKC vs ZFP36_S60 — LSCC

Per-sample scatter of ITPKC vs ZFP36_S60 in LSCC (Pearson r = 0.48).

Explore this scatter interactively →

Exploration