ITPK1-AS1

Across TCGA pan-cancer cohorts, ITPK1-AS1 RNA is linked to patient survival in 17 of 34 cancer types, making it the most broadly survival-associated ITPK1-AS1 data layer.

The strongest signal is observed in adrenocortical carcinoma (ACC), where higher ITPK1-AS1 RNA is associated with worse overall survival. In most high-consensus cancer types, elevated ITPK1-AS1 expression acts as an unfavorable survival marker, although some lineages such as OV and UVM show a favorable association.

ACC, COAD, and LIHC are the cancer types where ITPK1-AS1 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
ACC	OS	Median	All	0.398	0.748	<.001	95	view →
COAD	DFS	Median	III,IV	0.281	0.525	.001	66	view →
LIHC	DFS	Median	All	0.425	0.623	<.001	31	view →
OV	DFS	Quartile	III,IV	0.236	0.116	.007	16	view →
UVM	OS	Median	All	0.966	0.727	.014	15	view →
LGG	OS	Quartile	All	0.611	0.412	.008	12	view →
CESC	DFS	Quartile	All	0.585	0.755	.013	10	view →
CHOL	DFS	Tertile	III,IV	0.751	0.163	.024	9	view →
ESCA	OS	Tertile	II,III,IV	0.330	1.000	.027	9	view →
SKCM	OS	Quartile	IV	1.000	0.201	.017	7	view →
STAD	DFS	Quartile	IV	0.810	0.211	.039	6	view →
BLCA	OS	Median	III,IV	0.515	0.313	.037	4	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 17 lineages.

ITPK1-AS1–ACC (OS)

Open the ACC breakdown →